Answers to your questions

Lipotris™ is a gel that a doctor injects into the joint. The gel consists of hyaluronic acid and liposomes. It forms a smooth protective layer over the cartilage, so the joint moves more smoothly, and it also supports the joint from within.

• No. In addition to hyaluronic acid, Lipotris™ also contains liposomes: very small fat spheres that resemble the natural lubricants in your joint. They help the joint move more smoothly and ensure that the treatment not only works longer than a regular hyaluronic acid treatment, but also faster.

Liposomes are microscopically small, round fat spheres. Inside the joint they act like tiny ball bearings: the layer between the joint surfaces doesn’t just slide, it also rolls. The liposomes in Lipotris™ are fully synthetic, so they are not derived from animals or plants.

Each pre-filled syringe contains 44 mg of hyaluronic acid and 1.6 mg of liposomes in 2 ml of gel. The hyaluronic acid has a high molecular weight (1.2 to 3.2 MDa). A complete treatment consists of three syringes, 6 ml in total.

Most hyaluronic acid preparations are broken down by the body within a few weeks. Lipotris™ remains present in the joint for up to 13 weeks. This is thanks to the Lipotris Assembly Process (LAP™), a manufacturing method that makes the gel extra stable and protects it against rapid breakdown.

A complete treatment consists of three injections of 2 ml into the joint, spread over several visits. An injection only takes a few minutes, after which you can simply go home. In consultation with you, your doctor may deviate from this schedule. They will discuss this with you beforehand.

Your doctor decides on the schedule, tailored to your personal situation. In the clinical study of Lipotris™, the three injections were given 7 days apart.

The injections are always given by a medical professional, at one of the clinics that offer Lipotris™. View the clinics.

Lipotris™ is intended for people with osteoarthritis who suffer from pain, stiffness and difficulty moving. The clinical study was carried out in knee osteoarthritis. Whether the treatment is suitable for your joint is something to discuss with your doctor.

Lipotris™ is a good option when you suffer from pain, stiffness or difficulty moving, other treatments have not given sufficient results, a knee replacement is not (yet) an option, or when you are looking for a non-surgical treatment.

Your doctor will assess whether the treatment is appropriate in your situation. The full indications and contraindications can be found in the instructions for use.

Many patients notice the first improvement after about 2 weeks. The effect on pain and mobility can last for up to 2 years.

Lipotris™ remains present in the joint for up to 13 weeks and during that period sets off a long-lasting biological response. In clinical research, a significant improvement in the pain score (VAS) and the WOMAC score was still visible after 2 years. View the clinical results.

Lipotris™ is CE certified under the European MDR legislation for medical devices and has an excellent safety profile. The hyaluronic acid is produced through controlled bacterial fermentation and the liposomes are fully synthetic. The very high purity reduces the risk of a flare-up or pain after the injection.

As with any injection into a joint, the joint may be temporarily somewhat sensitive, warm or slightly swollen after the treatment. If symptoms persist or the joint becomes red, swollen and warm, contact your clinic. For full information, read the instructions for use.

In most cases this treatment is not reimbursed by your health insurer. Please check with your clinic or health insurer beforehand.

Lipotris™ is offered by clinics in the Netherlands and Belgium. View the overview of all clinics and make an appointment directly.

Healthcare providers can order Lipotris™ directly from Supportho Medical via supporthomedical.com.

You can download the instructions for use (IFU) here. Always consult the instructions for use for full information on indications, contraindications and safety.